Characteristics of Female Germline Stem Cells from Porcine Ovaries at Sexual Maturity
نویسندگان
چکیده
منابع مشابه
Isolation and characterization of string-forming female germline stem cells from ovaries of neonatal mice.
Germline stem cells are essential in the generation of both male and female gametes. In mammals, the male testis produces sperm throughout the entire lifetime, facilitated by testicular germline stem cells. Oocyte renewal ceases in postnatal or adult life in mammalian females, suggesting that germline stem cells are absent from the mammalian ovary. However, studies in mice, rats, and humans hav...
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Primordial germ cells (PGCs) are the precursors of reproductive gametes. They were first identified in the posterior region of embryos at the angle between the allantois and the wall of the yolk sac, and were shown to subsequently migrate into the forming gonadal ridges in early mouse and human embryos of both sexes (Eddy et al., 1981; Bendel-Stenzel et al., 1998). PGCs will eventually differen...
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Early menopause and infertility often occur in female cancer patients after chemotherapy (CTx). For these patients, oocyte/embryo cryopreservation or ovarian tissue cryopreservation is the current modality for fertility preservation. However, the above methods are limited in the long-term protection of ovarian function, especially for fertility preservation (very few females with cancer have ac...
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Zebrafish female germline stem cell (FGSC) cultures were generated from a transgenic line of fish that expresses Neo and DsRed under the control of the germ cell specific promoter, ziwi [Tg(ziwi:neo);Tg(ziwi:DsRed)]. Homogeneous FGSC cultures were established by G418 selection and continued to express ziwi for more than 6 weeks along with the germ cell markers nanos3, dnd, dazl and vasa. A key ...
متن کاملPurification of germline stem cells from adult mammalian ovaries: a step closer towards control of the female biological clock?
For decades it was believed that a non-renewable pool of oocyte-containing follicles is established in female mammals at birth. This cornerstone of reproductive biology was challenged 5 years ago by a study reporting on the presence of mitotically-active germ cells in juvenile and adult mouse ovaries. Additional findings presented in this study and others that followed further suggested that ma...
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ژورنال
عنوان ژورنال: Cell Transplantation
سال: 2018
ISSN: 0963-6897,1555-3892
DOI: 10.1177/0963689718784878